Compliance

» This 6-month open study evaluated the acceptability, tolerability and patient compliance with Calcia Calcium 500 mg chewable tablets taken twice daily for the prevention or treatment of osteoporosis in 1340 patients (median age 64 years)¹

» Acceptability was determined by the ease of taking the medication and its taste. Patient compliance was judged as good or excellent if patients were taking all tablets, or failed to take fewer than 10 per month¹

» After 6 months, taste was reported as good or excellent in 88.5% of patients, and taking the medication was described as easy or very easy in 99.4% of patients. Patient compliance was judged as good or excellent in 96% of patients after 6 months and was better in patients who were not taking any additional medication. Tolerability was good or excellent in 95.2% of patients after 6 months, the most frequently reported adverse events being dry mouth (1.4%) and gastralgia (0.7%)¹

» At the end of the trial, 84% of patients wished to continue to take Calcia Calcium 500 mg chewable tablets¹

¹ Lebas JF et al. Acceptabilité et tolérance du carbonate de calcium Théramex (Orocal 500 mg) lors d’un traitement au long cours. Le Concours Medical 1992; 4: 1-4.

» This 1-year, open-label, randomised, prospective study compared the effects of two calcium/vitamin D₃ treatments on femoral bone density and bone remodelling markers in 119 women (aged at least 70 years)

» Patients were randomised to receive either one chewable tablet of 500 mg elemental calcium and 400 IU vitamin D₃ (Calcia), or one sachet of 600 mg elemental calcium plus one chewable tablet of 400 IU vitamin D₃, morning and evening

» Compliance, defined as 'good' if patients took at least 80% of their 12-month treatment, was significantly better for those patients receiving Calcia Calcium/vitamin D₃ as one chewable tablet (83%) than for those taking calcium and vitamin D₃ as a separate sachet (63%) and tablet (59%) (p=0.006 for both comparisons)

» Compliance was significantly better for those patients taking Calcia than for those taking calcium and vitamin D₃ as separate preparations